SLU PP 332 1.3mg Peptide Pen boosts mitochondrial function and energy in approximately 26 doses per pen at 9 clicks per dose without muscle loss.
Product Name: SLU-PP-332 Pen
Formulation: 2.6 mL pre-filled pen
Clicks per Pen: 240
Total Amount: 1.3 mg SLU-PP-332
Supplied with: 6 sterile needles (extras available)
Key Benefits
- Fat Loss & Weight Management: Studies on obese mice showed significant reductions in fat mass gain. The drug prompts the body to use fat as its primary fuel source, essentially mimicking the metabolism of someone continuously exercising.
- Enhanced Endurance & Stamina: SLUPP-332 activates biological pathways that naturally respond to exercise, enabling normal-weight mice to run 70% longer and 45% further than untreated subjects.
- Mitochondrial Biogenesis: It promotes the growth and efficiency of mitochondria—the powerhouses of your cells—boosting cellular energy output and increasing overall oxygen capacity (VO2 max).
- Improved Metabolic Health: In models of metabolic syndrome, it has been shown to improve insulin sensitivity and decrease fat accumulation in the liver.
- Potential AntiAging & Cardioprotective Effects: Early research indicates potential in reducing ageassociated inflammatory markers, supporting cellular autophagy, and improving cardiac contractility
Description
SLU-PP-332 is a first-in-class synthetic small-molecule pan-agonist of estrogen-related receptors (ERRA, ERRẞ, and ERRY). It is a non-steroidal, non-endocrine-disrupting compound belonging to the class of ERR agonists. Chemical name: 4-hydroxy-N-(4-(2-(4-hydroxyphenyl)propan-2-yl)phenyl)benzamide (or structural analog thereof; exact proprietary structure is patented by Saint Louis University). SLU-PP-332 is orally bioavailable, metabolically stable, and designed to selectively activate ERRS without binding classical estrogen receptors (ERa/ERẞ).
Mechanism of Action
SLU-PP-332 binds directly to the ligand-binding domain of ERRA, ERRẞ, and ERRY, inducing conformational changes that promote coactivator recruitment (e.g., PGC-1a) and transcriptional activation of ERR target genes. Key downstream effects include:
- Upregulation of mitochondrial biogenesis and oxidative phosphorylation genes
- Increased expression of fatty acid oxidation enzymes and mitochondrial uncoupling proteins
- Enhanced type I (slow-twitch, oxidative) muscle fibre gene programs
- Improved exercise endurance capacity and metabolic flexibility
- Activation of energy expenditure pathways independent of classical estrogen signalling
- The compound induces an “exercise-like” molecular signature in skeletal muscle, liver, adipose tissue, and brain, mimicking many of the metabolic adaptations seen with chronic physical training.
Indications & Usage
SLU-PP-332 is used to support mitochondrial function, metabolic health, and exercise-like adaptations. It is indicated for:
- Enhancement of mitochondrial biogenesis and cellular energy production
- Promotion of fat oxidation, metabolic efficiency, and insulin sensitivity
- Support for endurance capacity, muscle oxidative phenotype, and recovery from metabolic stress
- Assistance in age-related or inactivity-related decline in mitochondrial and metabolic performance
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