Mito Boost delivers 60mg MOTS-c in up to 18 longevity-enhancing, performance-boosting doses.
Product Name: Mito Boost Pen
Formulation: 2.6 mL pre-filled pen
Clicks per Pen: 240
Total Amount: 60 mg MOTS–C
Supplied with: 6 sterile needles (extras available)
Key Benefits
- Metabolic Health: Improves insulin sensitivity and regulates glucose metabolism, making it highly studied for combating obesity and type 2 diabetes.
- Enhanced Athletic Performance: Mimics the cellular stress of exercise to increase stamina, spare muscle glycogen during prolonged activity, and optimize fat oxidation.
- Weight Management: Shifts the body to burn fat for fuel, helping to prevent dietinduced weight gain while preserving lean muscle mass.
- AntiAging & Cellular Protection: Interacts with the nucleus to reduce oxidative stress, lower chronic inflammation, and protect cardiovascular and bone health
Description
MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16–amino–acid mitochondrial–derived peptide (MDP) encoded within the mitochondrial 12S rRNA gene.
Chemical Structure
- Sequence: Met-Arg-Trp–Gln–Glu–Met–Gly–Tyr–Ile-Phe-Tyr–Pro–Arg–Lys–Leu-Arg (MRWQEMGYIFYPRKLR)
- Molecular weight: ~2,173 Da
- It is a linear peptide with no disulfide bonds or post–translational modifications in its native form.
Mechanism of Action
MOTS-C is transcribed and translated within mitochondria, then exported to the cytoplasm and nucleus where it acts as a retrograde signalling molecule. Its primary mechanism involves:
- Direct activation of AMP-activated protein kinase (AMPK)
- Increased expression of PGC-1a and downstream mitochondrial biogenesis genes
- Enhanced fatty acid ẞ-oxidation and glucose uptake
- Improvement of insulin sensitivity via reduced inflammatory signalling (↓ NF-kB, ↓ IL-6)
- Protection against metabolic stress, oxidative damage, and age-related mitochondrial decline
- Modulation of nuclear gene expression related to metabolism, proteostasis, and stress resistance
- By acting as a mitokine, MOTS-C coordinates mitochondrial-nuclear communication to optimize energy homeostasis, metabolic flexibility, and cellular resilience.
Indications & Usage
Mito Boost (MOTS-C) is used to support mitochondrial function and metabolic health. It is indicated for:
- Enhancement of mitochondrial biogenesis and energy production
- Support for fat oxidation, insulin sensitivity, and metabolic efficiency
- Assistance during age–related decline in physical performance and recovery
- Promotion of endurance, exercise capacity, and cellular resilience under metabolic stress
Powered by Precision MSSPT
Peptide Pen formulations set the standard for research peptide delivery in challenging environments. Powered by exclusive MSSPT, each pen combines buffers, antioxidants, and proprietary agents in a compact, user-friendly injector delivering strict control over pH, light, oxygen, oxidative factors, and moisture even under South Africa’s subtropical variability or the UAE’s extreme desert heat and humidity. This proprietary technology positions Peptide Pen as the premier choice for researchers in these regions: no mixing, no guesswork, and reliable, high-fidelity results despite demanding protocols and climates. Every Peptide Pen is built for exceptional durability, reliability, and performance, providing precision molecular stabilization in every dose, wherever your research takes you.
Mito Boost (MOTS-C)
Contraindications & Warnings
Do not use if you have:
- Known hypersensitivity to MOTS-C or any excipient
- Active malignancy (theoretical concern regarding cellular metabolism enhancement)
- Severe uncontrolled liver or kidney disease
- Pregnancy or breastfeeding
- Age under 18 years
Warnings
- Use only under medical supervision with periodic monitoring (e.g., glucose metabolism, liver function, clinical parameters).
- Not a substitute for lifestyle interventions or approved therapies for metabolic disorders. High doses may cause transient gastrointestinal discomfort or changes in energy levels.
- Discontinue immediately and seek medical attention if severe symptoms occur (e.g., severe abdominal pain, allergic reaction, or unexpected neurological changes).
Side Effects
MOTS-C is generally well tolerated across preclinical and early human studies. Reported reactions are uncommon and usually mild/transient, including:
- Mild injection-site irritation, redness, or itching
- Transient headache or light–headedness
- Temporary fatigue or changes in energy levels during initial use
- Rare mild gastrointestinal discomfort (nausea, bloating)
- If any severe or persistent symptoms occur (e.g., severe headache, abdominal pain, or allergic signs), discontinue use and contact your healthcare provider immediately.
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