Mito Boost delivers 60mg MOTS-c in up to 18 longevity-enhancing, performance-boosting doses.

Product Name: Mito Boost Pen

Formulation: 2.6 mL pre-filled pen

Clicks per Pen: 240

Total Amount: 60 mg MOTS–C

Supplied with: 6 sterile needles (extras available)

Key Benefits

Metabolic Health: Improves insulin sensitivity and regulates glucose metabolism, making it highly studied for combating obesity and type 2 diabetes.
Enhanced Athletic Performance: Mimics the cellular stress of exercise to increase stamina, spare muscle glycogen during prolonged activity, and optimize fat oxidation.
Weight Management: Shifts the body to burn fat for fuel, helping to prevent dietinduced weight gain while preserving lean muscle mass.
AntiAging & Cellular Protection: Interacts with the nucleus to reduce oxidative stress, lower chronic inflammation, and protect cardiovascular and bone health

Description

MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16–amino–acid mitochondrial–derived peptide (MDP) encoded within the mitochondrial 12S rRNA gene.

Chemical Structure

Sequence: Met-Arg-Trp–Gln–Glu–Met–Gly–Tyr–Ile-Phe-Tyr–Pro–Arg–Lys–Leu-Arg (MRWQEMGYIFYPRKLR)
Molecular weight: ~2,173 Da
It is a linear peptide with no disulfide bonds or post–translational modifications in its native form.

Mechanism of Action

MOTS-C is transcribed and translated within mitochondria, then exported to the cytoplasm and nucleus where it acts as a retrograde signalling molecule. Its primary mechanism involves:

Direct activation of AMP-activated protein kinase (AMPK)
Increased expression of PGC-1a and downstream mitochondrial biogenesis genes
Enhanced fatty acid ẞ-oxidation and glucose uptake
Improvement of insulin sensitivity via reduced inflammatory signalling (↓ NF-kB, ↓ IL-6)
Protection against metabolic stress, oxidative damage, and age-related mitochondrial decline
Modulation of nuclear gene expression related to metabolism, proteostasis, and stress resistance
By acting as a mitokine, MOTS-C coordinates mitochondrial-nuclear communication to optimize energy homeostasis, metabolic flexibility, and cellular resilience.

Indications & Usage

Mito Boost (MOTS-C) is used to support mitochondrial function and metabolic health. It is indicated for:

Enhancement of mitochondrial biogenesis and energy production
Support for fat oxidation, insulin sensitivity, and metabolic efficiency
Assistance during age–related decline in physical performance and recovery
Promotion of endurance, exercise capacity, and cellular resilience under metabolic stress

Peptide Pen formulations set the standard for research peptide delivery in challenging environments. Powered by exclusive MSSPT, each pen combines buffers, antioxidants, and proprietary agents in a compact, user-friendly injector delivering strict control over pH, light, oxygen, oxidative factors, and moisture even under South Africa’s subtropical variability or the UAE’s extreme desert heat and humidity. This proprietary technology positions Peptide Pen as the premier choice for researchers in these regions: no mixing, no guesswork, and reliable, high-fidelity results despite demanding protocols and climates. Every Peptide Pen is built for exceptional durability, reliability, and performance, providing precision molecular stabilization in every dose, wherever your research takes you.

Mito Boost (MOTS-C)

R 1 750,00

Quantity

Contraindications & Warnings

Do not use if you have:

Known hypersensitivity to MOTS-C or any excipient

Active malignancy (theoretical concern regarding cellular metabolism enhancement)

Severe uncontrolled liver or kidney disease

Pregnancy or breastfeeding

Age under 18 years

Warnings

Use only under medical supervision with periodic monitoring (e.g., glucose metabolism, liver function, clinical parameters).

Not a substitute for lifestyle interventions or approved therapies for metabolic disorders. High doses may cause transient gastrointestinal discomfort or changes in energy levels.

Discontinue immediately and seek medical attention if severe symptoms occur (e.g., severe abdominal pain, allergic reaction, or unexpected neurological changes).

Side Effects

MOTS-C is generally well tolerated across preclinical and early human studies. Reported reactions are uncommon and usually mild/transient, including:

Mild injection-site irritation, redness, or itching

Transient headache or light–headedness

Temporary fatigue or changes in energy levels during initial use

Rare mild gastrointestinal discomfort (nausea, bloating)

If any severe or persistent symptoms occur (e.g., severe headache, abdominal pain, or allergic signs), discontinue use and contact your healthcare provider immediately.
Dosage & Administration

Subcutaneous injection only.

Standard Dose: 5 mg (22 clicks) per injection

(delivers exactly 5 mg based on pen calibration)

Alternative Lower Dose: 3 mg (13 clicks) – for longevity/maintenance or sensitive protocols

Frequency: 2-3 times per week (e.g., Monday/Wednesday/Friday, or spaced around training/recovery days)

Timing: Morning or pre-workout to maximize energy, stamina, and recovery support

Cycle: Typically, 4-12 weeks on, followed by 4 weeks off to maintain efficacy

Optional Loading Phase: First 2-4 weeks: 5 mg 3×/week, then reduce to 2x/week or once weekly for maintenance

Administration Instructions

Wash hands and prepare a clean surface.

Attach a sterile needle.

Dial the required number of clicks (e.g., 22 clicks = 5 mg).

Clean injection site (abdomen or thigh) with alcohol swab. 5.Insert needle at 45-90° angle and inject slowly.

Withdraw needle, dispose safely, and cap the pen.

Rotate injection sites to minimize irritation.

Always inspect solution before use: Do not inject if cloudy, discoloured, or containing particles.

Storage & Handling

Store either in refrigerator (fridge); never freeze or in a cool dry place (≤25-30°C / 77-86°F). Keep pen capped and protected from light and heat.

After first use: Same storage conditions.

Keep out of reach of children.

Discard if expired or solution appears abnormal.

Mito Boost (MOTS-C)

Contraindications & Warnings

Dosage, Administration, Storage & Handling

Important notice

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